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Secondary Metabolites from Microorganisms
isolated by the HP Fiedler Group

Grecocyclines A and B

Producing organism: Streptomyces sp. Acta 1362

Habitat: terrestrial, rhizosphere; Crete, Greece
Screening method: HPLC-DAD
Biological activity: cytotoxic (A), protein tyrosine phosphatase 1B inhibiotor (B)


  • Paululat, T.; A. Kulik, H. Hausmann, A.D. Karagouni, H. Zinecker, J.F. Imhoff & H.-P. Fiedler. Eur. J. Org. Chem. 2010: 2344-2350, 2010

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