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Secondary Metabolites from Microorganisms
isolated by the HP Fiedler Group

Abyssomicins B, C, atrop C, D, G and H

Producing organism: Verrucosispora maris AB-18-032

Habitat: marine; Sea of Japan, sediment -289 m
Screening method: inhibition of para-aminobenzoic acid biosynthesis
Biological activity: antibacterial, inhibitior of para-aminobenzoic acid and folic acid biosynthesis (abyssomicin C, atrop-abyssomicin C)

References

  • Riedlinger, J.; A. Reicke, H. Zähner, B. Krismer, A.T. Bull, L.A. Maldonado, A.C. Ward, M. Goodfellow, B. Bister, D. Bischoff, R. Süssmuth & H.-P. Fiedler. J. Antibiotics 57: 271-279, 2004

    Bister, B.; D. Bischoff, M. Ströbele, J. Riedlinger, A. Reicke, F. Wolter, A.T. Bull, H. Zähner, H.-P. Fiedler & R.D.Süssmuth. Angew. Chem. Int. Ed. 43: 2574-2576, 2004

    Keller, S.; G. Nicholson, C. Drahl, E. Sorensen, H.-P. Fiedler & R.D. Süssmuth. J. Antibiotics 60: 391-394, 2007

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